This study investigates the determinants of business growth among indigenous small-scale businesses within Ndola's manufacturing food processing industry. Employing a descriptive research design, data was gathered from 50 indigenous small-scale businesses using a probability sampling method and structured questionnaires, with analysis conducted using Statistical Package for Social Sciences (SPSS). The objectives were to assess the effects of innovative capacity, entrepreneurial orientations, and market orientations on business growth and competitiveness. Regarding innovative capacity, the study found that enhancing it correlates with increased market share, improved product quality, and enhanced competitiveness, as perceived by respondents. The study revealed significant correlations between innovation, entrepreneurial orientation, and market orientation on business performance, with key statistics indicating: 100% of respondents reporting improved operational efficiency due to new technologies, 56% reporting increased market share and profitability from innovation, 50% reporting high risk-taking, 58% affirming customer needs understanding contributed to competitive advantage, suggesting innovation, entrepreneurial strategies, and market responsiveness drive growth for indigenous small-scale businesses in Ndola. In conclusion, the findings suggest that innovation, entrepreneurial strategies, and market responsiveness are key drivers of growth for indigenous small-scale businesses in Ndola. However, the effectiveness of these strategies varied across firms, with some experiencing profitability declines and limited market expansion. These mixed outcomes highlight the importance of integrating innovative efforts with a balanced approach to risk management and market orientation to achieve sustained growth and competitiveness.